CoQ10 Deficiency and Cellular Exhaustion

This is part of our ongoing The Best Kept Secrets to Healthy Aging spotlight. Each day, we will be posting some of the great information that’s packed into our book, The Best Kept Secrets to Healthy Aging.

Today’s topic:
CoQ10 Deficiency and “Cellular Exhaustion”

Individuals that have a deficiency of CoQ10 are inefficient in converting O2 to H2O and, therefore, are unable to generate adequate cellular energy. They suffer the consequences of “cellular exhaustion”, which may lead to the impairment of several normal physiological functions. These effects can be seen in the functioning of organs such as the brain, digestive tract, eyes and heart, and can also lead to decreases in energy levels and exercise capacity. As shown recently in the Archives of Neurology dietary supplementation with CoQ10 can restore the rate of mitochondrial respiration, muscle strength, coordination and exercise tolerance5, which highlights the ability of CoQ10 to support the healthy function of several systems by promoting cellular health.

Next Best Kept Secrets to Healthy Aging topic:
CoQ10, Endurance and “Energy”

References:
5. Di Lisa F, Menabo R, Canton M, Barile M, Bernardi P. Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart. J Biol Chem 2001;276:2571-2575.


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