Managing the Inflammatory Response with Antioxidant Vitamins

This is part of our ongoing The Best Kept Secrets to Healthy Aging spotlight. Each day, we will be posting some of the great information that’s packed into our book, The Best Kept Secrets to Healthy Aging.

Today’s topic:
Tips for Promoting a Normal Healthy, Balanced Inflammatory Response: Antioxidant Vitamins and Nutrients Normalize the Inflammatory Response

Vitamin C and vitamin E inhibit the oxidation of fats in the blood and stimulate the immune system to remove them from the circulation. These actions both protect the cardiovascular system and decrease the body’s overall inflammatory “tone.”4 In a study published in the Journal of Nutrition, it was found that the amount of vitamin C and E that older men and women consume is proportional to the amounts of fruit and vegetables they eat5 – eat more fruit and vegetables, eat more vitamins. But if you cannot eat enough fruits and vegetables every day, add supplements containing vitamins C and E to your daily diet. The antioxidant N-acetylcysteine also supports normalization of the inflammatory response in tissues.3,6 The findings of a published study demonstrate conclusively that because N-acetylcysteine can enter all cells it is a very effective and efficient antioxidant and supports a healthy inflammatory state throughout the body.7

Other powerful dietary antioxidants obtained from fruits and vegetables, such as the flavonoid quercetin and the stilbene resveratrol, also help the immune system support and maintain a healthy cardiovascular system. In addition, research in humans showed that pomegranate juice tones down and helps to stabilize levels of inflammation throughout the cardiovascular system.8 Nutritional science provides convincing evidence that in addition to beneficial dietary supplements, you can promote a healthy balance in your immune system by adding more fruits and vegetables to your diet.

Next Best Kept Secrets to Healthy Aging topic:
Tips for Promoting a Normal Healthy, Balanced Inflammatory Response: Fish Oil

3. Couillard C, Pomerleau S, Ruel G, Archer WR, Bergeron J, Couture P, Lamarche B, Bergeron N. Associations between hypertriglyceridemia, dietary fat intake, oxidative stress, and endothelial activation in men. Nutrition 2006;22:600-608.
4. Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB, Pahor M, Taaffe DR, Brach J, Rubin S, Harris TB. Physical activity, exercise, and inflammatory markers in older adults: Findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc 2004;52:1098-1104.
5. Gao X, Bermudez OI, Tucker KL. Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders. J Nutr 2004;134:913-918.
6. Li L, Sawamura T, Renier G. Glucose enhances human macrophage LOX-1 expression: Role for LOX-1 in glucose-induced macrophage foam cell formation. Circ Res 2004;94:892-901.
7. Sarkar D, Lebedeva IV, Emdad L, Kang DC, Baldwin AS Jr, Fisher PB. Human polynucleotide phosphorylase (hPNPaseold-35): A potential link between aging and inflammation. Cancer Res 2004;64:7473- 7478.

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