Nutrim Daily, New from Purity Products

Nutrim® was developed by a USDA Agricultural Research Service Hall of Fame scientist to make it easier to get the benefits of oats to help promote a healthy cholesterol level. The patented process optimizes Nutrim®’s viscosity, which is believed to be the key to Nutrim®’s success. For over 40 years, clinical research has shown oats and oat bran can help maintain healthy cholesterol levels.

Nutrim is made from 100% oat bran. Unlike oats from the grocery store, Nutrim concentrates the most powerful part of oat bran and beta-glucans. Beta-glucans are the soluble (water-friendly) portion of oat bran. Because beta-glucans mix so well in solution, they can be added to all types of foods and beverages, like juices or sauces.

  • USDA Developed
  • Maintains normal blood cholesterol levels with 4 mechanisms of action*
  • Supports healthy blood sugar, normal appetite and promotes digestive function*
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MuffinStop, New from Purity Products

MuffinStop™ – Stop the Top!™

While the world waits for the elusive weight loss miracle pill, for now consider Purity’s new MuffinStop™. MuffinStop™ was shown in two randomized, double-blind, placebo-controlled clinical studies to be an effective part of a responsible weight management program*. MuffinStop™ is a combination of two traditionally used botanical ingredients, Sphaeranthus indicus and Garcinia mangostana, now fused together to create one of the most innovative weight loss products the supplement industry has to offer.

Real Results
Research shows that MuffinStop™ may start helping people reach their weight-management goals in as little as two weeks. The research also showed that participants receiving MuffinStop™ instead of the placebo experienced interesting results in the hips and waist, two target areas where fat is often stored.

Two human clinical studies that included a 2,000 calorie diet, exercise, and supplementation with MuffinStop™ showed:

  • Supports weight-loss with results showing in as little as 2 weeks*
  • Supports reduction in waist size*
  • Supports reduction in hip size*
  • May help the body burn fat*
  • Supports a healthy adiponectin level*
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Drink Green Tea to Keep that Belly in Line

This is part of our ongoing The Best Kept Secrets to Healthy Aging spotlight. Each day, we will be posting some of the great information that’s packed into our book, The Best Kept Secrets to Healthy Aging.

Today’s topic:
Drink Tea to Keep that Belly in Line

In men and women, the degree of body fat, whether expressed as percent body fat or the ratio of waist circumference to hip circumference, tends to decrease as green tea intake increases.22 Green tea contributes to the maintenance of healthy body weight in several ways.

One of the least appreciated properties of green tea is its ability to limit the absorption of the fat taken in from the diet. Green tea catechins (especially EGCG) interfere with the lipase (fat-digesting) enzymes in the stomach and small intestine. The resulting incomplete digestion of fats produces some lipid droplets that are not able to enter intestinal cells and that therefore remain unabsorbed. These effects have produced significant decreases in the absorption of dietary fats by rats consuming green tea. While it is not known how effective green tea is in blocking fat absorption in humans, any interference with the normally highly efficient digestion and absorption of dietary fats could figure prominently in any effort to manage weight effectively.

In addition to decreasing the efficiency of absorption of fatty acids from the diet, green tea catechins interfere with the production of fat for storage in adipose tissue depots. Green tea leaf extract rich in EGCG, as well as purified EGCG itself, reduces the activity of fatty acid synthase, the enzyme that controls how rapidly the body produces fat for storage. This effect is consistent with a body of literature reviewed recently in the journal Molecular Nutrition and Food Research that shows how EGCG inhibits new fat formation (“lipogenesis”) and fat storage within adipocytes.23 Tea helps to absorb less fat from the diet and can directly interfere with the storage of fat in adipocytes, a dual mechanism for supporting healthy body weight.

The dominant green tea catechin, EGCG, also entices the body to shift some of its manner of producing energy from glucoseburning to fat-burning. There are two ways to accomplish this and EGCG seems to do both. First, if the amount of glucose available to tissues, especially the skeletal muscles, is reduced, then more fat must be metabolized to carbon dioxide and water in order to satisfy energy needs. During times when glucose is in short supply, the liver synthesizes glucose from a variety of precursors, including amino acids released by muscle cells. The first enzyme in this synthetic (“gluconeogenic”) pathway, phosphoenolpyruvate carboxykinase (PEPCK), is inhibited by EGCG. Blocking this enzyme reduces the rate of formation of new glucose, requiring cells to switch to burning fat for energy.

In an example of exquisite biochemical coordination, EGCG also stimulates the conversion of fatty acids to energy. In cell culture studies, EGCG has increased the rate of utilization of fatty acid breakdown products instead of glucose to produce energy. In a series of experiments, mice, often studied because the way they obtain energy is pretty much the same as the way humans do, have responded to the addition of catechin-rich green tea extract to a high-fat diet with less weight gain and less fat accumulation within their bodies than mice fed the same high-fat diet but not fed catechins, despite eating just as much. This phenomenon has been studied in depth. In a recent study dietary supplementation of exercising mice with tea catechins forced skeletal muscles to switch from using their glycogen reserves as energy sources to increasing their reliance on burning fats from adipose depots.24 This “switch” is so reproducible that the researchers can predict when it will happen. The powerful phytonutrients (catechins) in green tea and green tea extract can recruit muscles to help stored fat get used up faster!

In humans, such a shift from glucose-burning to fat-burning will be seen as an increase in heat production (or thermogenesis). In a convincing demonstration of the fat-burning, thermogenic effects of green tea catechins, 24-hour heat production was measured in healthy lean to overweight young men during days in which they remained essentially at rest and consumed identical diets, no caffeine-containing foods or beverages, and either a placebo, 150 mg of caffeine alone or 150 mg of caffeine plus 270 mg of EGCG and 105 mg of other mixed catechins.25 These investigators observed that the consumption of placebo or 150 mg of supplemental caffeine alone during a 12-hour period failed to affect the utilization of fat or glucose to supply energy. In contrast, the consumption of green tea catechins during a 12-hour period increased same-day 24-hour total energy expenditure and heat production. This increase in energy usage was caused by increased fat-burning and decreased use of glucose for fuel.

Because under the conditions of this experiment all energy expenditure was essentially “resting” energy expenditure, the catechin-induced increase in resting energy expenditure reflects enhanced thermogenesis. That is, more heat production as a “byproduct” of energy production. Since increased heat production to satisfy the same energy demand means that the efficiency of energy production decreased, more stored energy needed to be “burned” – accelerating the rate at which energy stored in fat depots would become depleted. Of course, as stored fat becomes depleted, both body weight and fat depot size decrease.

The increase in fat utilization in this experiment, which was minimized by keeping the subjects in a “resting” state, could result in the loss of one pound of excess body weight in 1 to 2 months and a loss of 6 to 12 pounds in a year. Consistent with this rough prediction, overweight adults consuming 270 mg of EGCG daily for 3 months experienced an average loss of 4.6% of total body weight, with an average decrease in waist circumference of 4.5%.26 This thermogenic effect of green tea catechins, when combined with a healthy diet and exercise, could be extremely beneficial for those looking to support weight management efforts.

Beneficial results also were obtained in a “gold standard,” randomized placebo-controlled clinical trial, published recently in the American Journal of Clinical Nutrition.27 In this study healthy men supplemented their diets with either 22 mg or 690 mg of total catechins daily for 12 weeks. At the end of the experiment, the men who were consuming 690 mg of total catechins daily had lost more weight, more inches off their waist, more total body fat and more abdominal fat.

What about Stress and Abdominal Fat?

A growing body of evidence indicates that in both men and women, stress and mood issues are associated with increased abdominal fat storage and a larger waistline. How is stress and belly fat connected?

Stress can increase the secretion of a hormone called cortisol. This hormone increases the rate of fat accumulation by abdominal fat cells. Even among healthy individuals, repeated episodes of stress-related cortisol secretion is implicated in increased abdominal fat.28

What Can Green Tea Do About It?

Green tea contains an unusual amino acid – L-theanine. This amino acid comprises up to 2.5% of the total dry weight of unfermented green tea leaves, is absorbed efficiently and can enter the brain from the blood. Within the brain, L-theanine exerts relaxing physiologic effects. In so doing, L-theanine may act to reduce perceptions of stress with possible beneficial effects on abdominal fat formation. For example, mice fed L-theanine have gained less weight and accumulated less abdominal fat.29,30 By supporting the body’s stress response, green tea and green tea extracts containing L-theanine can make important contributions to healthy weight maintenance.

Next Best Kept Secrets to Healthy Aging topic:
Tea Helps Keep Healthy Kidneys Healthy

22. Wu CH, Lu FH, Chang CS, Chang TC, Wang RH, Chang CJ. Relationship among habitual tea consumption, percent body fat, and body fat distribution. Obes Res 2003;11:1088-1095.
23. Wolfram S, Wang Y, Thielecke F. Anti-obesity effects of green tea: From bedside to bench. Mol Nutr Food Res 2006;50:176-187.
24. Murase T, Haramizu S, Shimotoyodome A, Tokimitsu I, Hase T. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. Am J Physiol Regul Integr Comp Physiol 2006;290:R1550-R1556.
25. Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr 1999;70:1040-1045.
26. Chantre P, Lairon D. Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity. Phytomedicine 2002;9:3-8.
27. Nagao T, Komine Y, Soga S, Meguro S, Hase T, Tanaka Y, Tokimitsu I. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr 2005;81:122-129.
28. Rosmond R, Dallman MF, Bjorntorp P. Stress-related cortisol secretion in men: Relationships with abdominal obesity and endocrine, metabolic and hemodynamic abnormalities. J Clin Endocrinol Metab 1998;83:1853-1859.
29. Juneja LR, Chu D-C, Okubo T, Nagato Y, Yokogoshi H. L-theanine, a unique amino acid of green tea and its relaxation effect in humans. Trends Food Sci Technol 1999;10:199-204.
30. Zheng G, Sayama K, Okubo T, Juneja LR, Oguni I. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo 2004;18:55-62.

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